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What Is LI4 (Hegu)?
LI4 (Hegu, 合谷) is the 4th acupoint of the Large Intestine meridian under WHO standard meridian point nomenclature. In traditional Chinese medicine, it is referred to as “Hegu for the face and mouth” and is used as the representative treatment point for diseases around the face and mouth.
Precise Location
With the thumb and index finger spread apart, it is located in the hollow on the thumb side, at the midpoint of the 2nd metacarpal (index finger bone). When grasped between the thumb and index finger of the other hand, the most tender spot is Hegu.
Benefits and Effects
- Headache relief — Reduces pain with 3–5 minutes of acupressure for migraines and tension headaches
- Toothache relief — Used for emergency pain relief before dental treatment
- Improvement of cold symptoms — Relieves nasal congestion and sore throat
- Stress relief — Relaxation effect through autonomic nervous system regulation
- Promotes digestion — As a Large Intestine meridian acupoint, helps with constipation
Acupressure Technique Guide
Step 1: Locate LI4
Spread your thumb and index finger apart and find the highest point of the muscle between them. Press with the opposite thumb to find the spot that feels sore and achy — that’s Hegu.
Step 2: Press with Your Thumb
Press LI4 firmly with the opposite thumb for 3–5 seconds, then release slowly. Apply medium pressure (slightly sore).
Step 3: Repeat with Breathing
Press while exhaling, release while inhaling. Do 10–15 times per hand, alternating both hands, 2–3 times daily.
Synergistic Combinations
| Combination | Acupoints | Target Symptoms |
|---|---|---|
| Four Gates (Siguan) | LI4 (Hegu) + LR3 (Taichong) | Headaches, stress, high blood pressure |
| Cold combo | LI4 (Hegu) + GB20 (Fengchi) | Cold, nasal congestion, fever |
| Digestion combo | LI4 (Hegu) + ST36 (Zusanli) | Indigestion, constipation |
Precautions
LI4 can stimulate uterine contractions in pregnant women — absolutely do not press it during pregnancy. Avoid areas with skin wounds, and refrain from strong acupressure within 30 minutes after a meal.
Frequently Asked Questions
Where is LI4 (Hegu) located?
LI4 (Hegu) is located in the hollow between the thumb and index finger, at the midpoint of the 2nd metacarpal bone.
How many times a day should I press LI4?
Press 2–3 times a day, alternating both hands for 30 seconds to 1 minute each time.
Can pregnant women press LI4?
LI4 can stimulate uterine contractions in pregnant women and should be avoided during pregnancy.
What acupoints work well with LI4?
Pressing it together with LR3 (Taichong) forms the ‘Four Gates’ (Siguan) combination, which is effective for headaches and stress.
Are there any side effects of pressing LI4?
There are almost no side effects with appropriate pressure, but excessive stimulation may cause bruising.

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